Quality of services for remote control in High Energy Physics experiments: a case study

Abstract The development of new advanced applications and the evolution in networking are two related processes which greatly benefit from two-way exchanges and from progress in both fields. In this study we show how mission-oriented networked applications can be effectively deployed for research purposes if coupled to the support of Quality of Service (QoS) in IP networks. QoS is one of the latest research topics in network engineering. In this article we focus on two specific examples of networked applications: remote instrumentation control and remote display of analysis data when applied for the support of experiments in the high energy physics field. In this paper we focus on the application requirements: the availability of a reliable transmission channel, limited one-way delay for timely interactions between servers and clients and fairness in network resources allocation in case of contention. The above-mentioned requirements can be addressed through the support of QoS, i.e. through the differential treatment of packets on the end-to-end data path. Several technologies and protocols for QoS support in packet networks have been devised during the last years by the research community. In this study we focus on the Differentiated Services (diffserv) approach, an architecture characterized by high scalability, flexibility and interoperability. In this paper we identify the application requirements and we quantitatively specify the corresponding service profiles. The diffserv network architecture needed to support the services is defined in terms of functional blocks (policing, classification, marking and scheduling) and of their placement in the network. Finally, for each of them the configuration best suited to remote control support is defined

Ocorrência de incontinência urinária em cadelas castradas no Hospital Veterinário da Universidade Anhembi-Morumbi, São Paulo, Brasil

Incontinência urinária (IU) pode ocorrer após castração de cadelas, quando há diminuição nos níveis circulantes de hormônios esteroides e aumento nos de gonadotrofinas, além de alteração funcional no esfíncter uretral. Para determinar a ocorrência da IU em cadelas castradas no Hospital Veterinário da Universidade Anhembi-Morumbi, os prontuários de cadelas esterilizadas no período 2002-2009 foram analisados de agosto de 2010 a março de 2011. Foi feito contato telefônico com os proprietários para investigar um possível desenvolvimento de IU após a castração. Nesse período, foram contatados osproprietários de 227 cadelas. Destas, 73 (32,2%) vieram a óbito sem sintoma de IU pós-castração, 146 (64,3%) não apresentaram IU e oito (3,5%) desenvolveram IU no período de 3,8 ± 1,6 anos após castração

DEPLOYMENT OF NATIVE IP MULTICAST ROUTING SERVICES ON THE ITALIAN ACADEMIC AND RESEARCH NETWORK

In 1993 the GARR (Italian Academic and Research Network) was connected to MBONE (worldwide IP multicast enabled network backbone). Since then, and especially in the last few years, this network has been used to test and develop new IP multicast routing protocols and applications. However it was a tunnel-based solution, not suitable for taking advantage of the new potential of IP multicast nor for use by a large community. This paper describes the work done for a migration to a native IP multicast routing deployment, highlighting the solutions adopted when dealing with the implementation problems and the complex wide area network management. The aim of this work is also to ensure a native IP multicast connection with the other Research Networks and the rest of Internet

Rete GARR-B: Piano di routing IP multicast

The IP multicast was introduced in the GARR network (Italian Network for University and Scientific Community) in 1993 with the connection to Mbone (worldwide virtual multicast network). Since then the Italian Mbone developed constantly allowing the test of protocols and applications. Nevertheless the original Mbone structure is not suitable for an efficient utilization of multicast potentialities and advantages, preventing from exploiting all the services on a large scale; moreover it doesn\u27t allow an interconnection with those ISP which are enabling multicast in their networks but with different technical solutions. This document, after a description of the limits of the present Mbone on GARR, proposes the steps for an updating plane: - IP multicast implementation on the production routers of the backbone, using the PIM-SM protocol; - choice and configuration of the Rendez-Vous Points; - definition of IP multicast boundary routers; - bandwidth limitation; - inter-domain routing (MSDP and MBGP); - international multicast connections. The document deals with some of IP multicast management tools, as well.L\u27introduzione del multicast IP sulla rete GARR (Rete per l\u27Universit? e la Ricerca Scientifica Italiana) risale al 1993 con la prima connessione a Mbone (rete virtuale multicast mondiale). Da allora c\u27e\u27 stato un costante sviluppo sulla Mbone italiana che ha reso possibile la sperimentazione di protocolli e applicativi. Tuttavia la struttura originaria di Mbone non consente un utilizzo efficace delle potenzialita\u27 e dei vantaggi del multicast, precludendo la possibilita\u27 di sfruttarne appieno i servizi su larga scala; cosi\u27 come non consente l\u27interconnessione con quegli ISP che stanno gia\u27 abilitando le loro reti al multicast con soluzioni tecniche diverse. Questo documento, dopo una descrizione dei limiti dell\u27attuale Mbone sul GARR, ne propone le fasi necessarie per un piano di aggiornamento: - implementazione di IP multicast sulla dorsale sui router di produzione con protocollo PIM-SM; - scelta e configurazione dei Rendez-Vous Point; - definizione delle frontiere amministrative (boundary router); - limitazioni di banda; - inter-domain routing (MSDP e MBGP); - connessioni multicast internazionali. Il documento contiene anche un accenno ad alcuni degli strumenti utilizzabili per la gestione dell?IP multicast

The Open Science Commons for the European Research Area

Nowadays, research practice in all scientific disciplines is increasingly, and in many cases exclusively, data driven. Knowledge of how to use tools to manipulate research data, and the availability of e-Infrastructures to support them for data storage, processing, analysis and preservation, is fundamental. In parallel, new types of communities are forming around interests in digital tools, computing facilities and data repositories. By making infrastructure services, community engagement and training inseparable, existing communities can be empowered by new ways of doing research, and new communities can be created around tools and data. Europe is ideally positioned to become a world leader as provider of research data for the benefit of research communities and the wider economy and society. Europe would benefit from an integrated infrastructure where data and computing services for big data can be easily shared and reused. This is particularly challenging in EO given the volumes and variety of the data that make scalable access difficult, if not impossible, to individual researchers and small groups (i.e. to the so-called long tail of science). To overcome this limitation, as part of the European Commission Digital Single Market strategy, the European Open Science Cloud (EOSC) initiative was launched in April 2016, with the final aim to realise the European Research Area (ERA) and raise research to the next level. It promotes not only scientific excellence and data reuse, but also job growth and increased competitiveness in Europe, and results in Europe-wide cost efficiencies in scientific infrastructure through the promotion of interoperability on an unprecedented scale. This chapter analyses existing barriers to achieve this aim and proposes the Open Science Commons as the fundamental principles to create an EOSC able to offer an integrated infrastructure for the depositing, sharing and reuse of big data, including Earth Observation (EO) data, leveraging and enhancing the current e-Infrastructure landscape, through standardization, interoperability, policy and governance. Finally, it is shown how an EOSC built on e-Infrastructures can improve the discovery, retrieval and processing capabilities of EO data, offering virtualised access to geographically distributed data and the computing necessary to manipulate and manage large volumes. Well-established e-Infrastructure services could provide a set of reusable components to accelerate the development of exploitation platforms for satellite data solving common problems, such as user authentication and authorisation, monitoring or accounting

Mechanisms of nerve damage in neuropathies associated with hematological diseases: lesson from nerve biopsies

Despite the introduction of non-invasive techniques in the study of peripheral neuropathies, sural nerve biopsy remains the gold standard for the diagnosis of several neuropathies, including vasculitic neuropathy and neurolymphomatosis. Besides its diagnostic role, sural nerve biopsy has helped to shed light on the pathogenic mechanisms of different neuropathies. In the present review, we discuss how pathological findings helped understand the mechanisms of polyneuropathies complicating hematological diseases

Intestinal parasites in Rupicapra spp. populations: study in the framework of the relevant italian project (PRIN)

Intestinal parasites can seriously threaten the performances and well-being of wild ungulates. In this study, we investigated the occurrence and parasitic burden of protozoans and gastro-intestinal helminths (GIH) in Rupicapra spp. From September 2013 to January 2016, 352 fresh fecal samples were collected from Rupicapra rupicapra rupicapra in the Alps (N=262) and from Rupicapra pyrenaica ornata in the Apennines (N=90). Samples were examined using standard copro-parasitological methods for Eimeria and GIH and an immunofluorescence test for Cryptosporidium and Giardia duodenalis. Parts of gp60 and ssRNA/gdh/βgiardin genes were used to identify these protozoa species/genotypes. In R.r.rupicapra and in R.p.ornata, 7 and 6 parasite taxa were identified, respectively, with a mean number of 1.7 species/host (min-max 0-5) and 2.05 (min-max: 0-4), respectively. Overall, 85.3% (95%, C.I.=81.5-89.1) of the animals investigated scored microscopically positive to Eimeria spp. with a mean intensity of emission (m.i.e.) of up to 776 o.p.g.; 5.4% (95%, C.I.=3.07.7) were positive to G. duodenalis and 82% (95%, C.I. 77.91-86.15) to GIH with a m.i.e. of up to 147 e.p.g. Prevalence in R.r.rupicapra was 81.2% with a m.i.e. of 380 o.p.g. for Eimeria, 6.87% for Giardia, and 77.45% for GIH with a m.i.e. of 142 e.p.g. Prevalence in R.p.ornata was 94.4% with m.i.e. of 1,093 o.p.g. for Eimeria, 1.1% for G.duodenalis, and 94.4% for GIH with a m.i.e. of 151 e.p.g. Assemblages A/AI and E were identified in R.r.rupicapra and assemblage A/AIII in R.p.ornata. None of the animals tested positive for Cryptosporidium. The results show that the prevalence of Eimeria, G.duodenalis and GIH in both host species is nonnegligible, with a significantly higher parasitic burden in R.p.ornata. The detection of G. duodenalis in Rupicapra spp. is noteworthy. This study updates the data on parasitic fauna of these wild bovids. The impact of these parasites on chamois population dynamics will be inferred from the results/variables obtained throughout the entire interdisciplinary project

The SKA view of cool-core clusters: evolution of radio mini-halos and AGN feedback

In about 70% of the population of relaxed, cool-core galaxy clusters, the brightest cluster galaxy (BCG) is radio loud, showing non-thermal radio jets and lobes ejected by the central active galactic nucleus (AGN). In recent years such relativistic plasma has been unambiguously shown to interact with the surrounding thermal intra-cluster medium (ICM) thanks to spectacular images where the lobe radio emission is observed to fill the cavities in the X-ray-emitting gas. This `radio feedback' phenomenon is widespread and is critical to understand the physics of the inner regions of galaxy clusters and the properties of the central BCG. At the same time, mechanically-powerful AGN are likely to drive turbulence in the central ICM which may also play a role for the origin of non-thermal emission on cluster-scales. Diffuse non-thermal emission has been observed in a number of cool-core clusters in the form of a radio mini-halo surrounding the radio-loud BCG on scales comparable to that of the cooling region. Large mini-halo samples are necessary to establish their origin and connection with the cluster thermal properties and dynamics, especially in light of future X-ray characterization of the cluster cores as it is expected by Athena-XIFU. We show that All-Sky reference survey at Band 2 with SKA1 at confusion limit (rms ~2 {\mu}Jy per beam) has the potential to detect up to ~620 mini-halos at redshift z<0.6, whereas Deep Tier reference surveys at Band 1/2 with SKA1 at sub-arcsec resolution (rms ~0.2 {\mu}Jy per beam) will allow a complete census of the radio-loud BCGs at any redshift down to a 1.4 GHz power of 10^{22} W/Hz. We further anticipate that SKA2 might detect up to ~1900 new mini-halos at redshift z<0.6 and characterize the radio-mode AGN feedback in every cluster and group up to redshift z ~1.7 (the highest-z where virialized clusters are currently detected).Comment: 17 pages, 5 figures. To appear as part of 'Continuum Science' in Proceedings of "Advancing Astrophysics with the SKA (AASKA14)", PoS(AASKA14)07

Flu Vaccination in Liguria and in Italy: data from the Health Surveillance Systems ?PASSI? and ?PASSI d?Argento?

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